Soft Condensed Matter Group

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Janina Lange

Dr. rer. nat. Janina Lange



Collective cell migration, single cell arrays


Geschwister-Scholl-Platz 1
80539 München

Room: NZ033
Phone: +49 (0)89 2180 1453

Work group

Rädler group


J. R. Lange, C. Metzner, S. Richter, W. Schneider, M. Spermann, T. Kolb, G. Whyte, and B.
Fabry, “Unbiased high-precision cell mechanical measurements with microconstrictions,” Biophys-
ical Journal, vol. 112, no. 7, pp. 1472-1480, 2017.

J. R. Lange, J. L. Alonso, and W. H. Goldmann, “Influence of avb3 integrin on the mechanical
properties and the morphology of M21 and K562 cells,” Biochemical and biophysical research com-
munications, vol. 478, pp. 1280-1285, 2016.

T. F. Bartsch, M. D. Kochanczyk, E. N. Lissek, J. R. Lange, and E.-L. Florin, “Nanoscopic imag-
ing of thick, heterogeneous soft-matter structures in aqueous solution,” Nature Communications,
vol. 7:12729, 2016.

L. A. Lautscham, C. Kämmerer, J. R. Lange, T. Kolb, C. Mark, A. Schilling, P. L. Strissel, R.
Strick, C. Gluth, A. C. Rowat, C. Metzner, and B. Fabry, “Migration in confined 3D environments
is determined by a combination of adhesiveness, nuclear volume, contractility, and cell stiffness,”
Biophysical Journal, vol. 109, no. 5, pp. 900-913, 2015.

J. R. Lange, J. Steinwachs, T. Kolb, L. A. Lautscham, I. Harder, G. Whyte, and B. Fabry,
Microconstriction arrays for high-throughput quantitative measurements of cell mechanical prop-
erties,” Biophysical Journal, vol. 109, no. 1, pp. 26-34, 2015.

N. Lang, S. Münster, C. Metzner, P. Krauss, J. R. Lange, S. Schürmann, K. E. Aifantis, O.
Friedrich, and B. Fabry, “Estimating the 3D pore size distribution of biopolymer networks from
directionally biased data,” Biophysical Journal, vol. 105, no. 9, 1967-1975, 2013.

J. R. Lange, V. Auernheimer, P. L. Strissel, and W. H. Goldmann, “Influence of focal adhesion
kinase on the mechanical behavior of cell populations,” Biochemical and biophysical research com-
munications, vol. 436, pp. 246-251, 2013.

J. R. Lange, and B. Fabry, “Cell and tissue mechanics in cell migration,” Experimental Cell
Research, vol. 319, pp. 2418-2423, 2013.

P. Krauss, C. Metzner, J. R. Lange, N. Lang, and B. Fabry, “Parameter-free binarization and
skeletonization of fiber networks from confocal image stacks,” PLoS ONE vol. 7: e36575, 2012.