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Tim Liedl's Publications


E.-M. Roller, L. V. Besteiro, C. Pupp, L. Khosravi Khorashad, A. O. Govorov, T. LiedL
Hotspot-mediated non-dissipative and ultrafast plasmon passage
Nature Physics doi:10.1038/nphys4120 (2017) article

S. Sellner, S. Kocabey, T. Zhang, K. Nekolla, S. Hutten, F. Krombach, T. Liedl, M. Rehberg
Dexamethasone-conjugated DNA nanotubes as anti-inflammatory agents in vivo
Biomaterials 134, 78–90 (2017) article

A. M. Maier, W. Bae, D. Schiffels, J. F. Emmerig, M. Schiff, T. Liedl
Self-assembled DNA tubes forming helices of controlled diameter and chirality
ACS Nano doi: 10.1021/acsnano.6b05602 (2017) article


F. Nicoli, M. K. Roos, E. A. Hemmi, M. Di Antonio, R. de Vivie-Riedle, T. Liedl
Proximity-induced H-aggregation of Cyanine dyes on DNA duplexes
J. Phys. Chem. A DOI: 10.1021/acs.jpca.6b10939 (2016) article

P. C. Nickels, B. Wünsch, P. Holzmeister, W. Bae, L. M. Kneer, D. Grohmann, P. Tinnefeld, T. Liedl
Molecular force spectroscopy with a DNA origami–based nanoscopic force clamp
Science 354, 6310, pp. 305-307 (2016) article

S. Simoncelli, E-M. Roller, P. Urban, R. Schreiber, A. J. Turberfield, T. Liedl, T. Lohmüller
Quantitative single molecule surface-enhanced Raman scattering by optohermal tuning of DNA origami-assembled plasmonic nanoantennas
ACS Nano DOI: 10.1021/acsnano.6b05276 (2016) get article

E-M. Roller, C. Argyropolous, A. Höglee, T. Liedl, M. Pilo-Pais
Plasmon-Exciton coupling using DNA templates
Nano Letters 16, 5962 (2016) get article

S. Fischer, C. Hartl, K. Frank, J. Rädler, T. Liedl, B. Nickel
Shape and inter-helical spacing of DNA origami nanostructures studied by small angle X-ray scattering
Nano Letters 16, 4282 (2016) get article

Nickels, P. C., Høiberg, H. C., Simmel, S. S., Holzmeister, P., Tinnefeld, P., Liedl, T.
DNA Origami Seesaws as Comparative Binding Assay
ChemBioChem, doi: 10.1002/cbic.201600059 (2016) (get article)

A. M. Maier, C. Weig, P. Oswald, E. Frey, P. Fischer, T. Liedl
Magnetic Propulsion of Microswimmers with DNA-Based Flagellar Bundles
Nano Letters, 16 (2), 906-910 (2016) (get article)

K. Martens, T. Funck, S. Kempter, E.-M. Roller, T. Liedl, B. M. Blaschke, P. Knecht, J. A. Garrido, B. Zhang, H. Kitzerow
Alignment and Graphene-Assisted Decoration of Lyotropic Chromonic Liquid Crystals Containing DNA Origami Nanostructures
Small. doi:10.1002/smll.201503382 (2016) (get article)


T. Zhang, A. Neumann, J. Lindlau, Y. Wu, G. Pramanik, B. Naydenov, F. Jelezko, F. Schüder, S. Huber, M. Huber, F. Stehr, A. Högele, T. Weil, T. Liedl
DNA-based Self-Assembly of Fluorescent Nanodiamonds
J. Am. Chem. Soc. 137, 9776-9779 (2015) (get article)

B. Nickel & T. Liedl
DNA-linked superlattices get into shape (Commentary)
Nature Materials 14, 746-749 (2015) (get article)

T. Liedl
Pathfinder for DNA constructs (News & Views)
Nature 523, 412-413 (2015) (get article)

Cassinelli, V., Oberleitner, B., Sobotta, J., Nickels, P., Grossi, G., Kempter, S., Frischmuth, T., Liedl, T., Manetto, A.
One-Step Formation of “Chain-Armor”-Stabilized DNA Nanostructures
Angewandte Chemie - International Edition, 54 (27), 7795-7798 (2015) (get article)
Research highlight in: Nature Materials 14, 654 (2015) (get article)

Kocabey, S., Kempter, S., List, J., Xing, Y., Bae, W., Schiffels, D., Shih, W. M., Simmel, F. C., Liedl, T. 
Membrane-Assisted Growth of DNA Origami Nanostructure Arrays
ACS Nano 9 (4), 3530-3539 (get article)

Göpfrich, K., Zettl, T., Meijering, A. E. C., Hernández-Ainsa, S., Kocabey, S., Liedl, T., Keyser, U. F.
DNA-Tile Structures Induce Ionic Currents through Lipid Membranes
Nano Letters 15, 3134-3138 (2015) (get article)

Sellner, S., Kocabey, S., Nekolla, K., Krombach, F., Liedl, T., Rehberg, M.
DNA nanotubes as intracellular delivery vehicles in vivo
Biomaterials 53, 453-463 (2015) (

Roller, E.-M., Khorashad, L. K., Fedoruk, M., Schreiber, R., Govorov, A. O., Liedl, T.
DNA-assembled nanoparticle rings exhibit electric and magnetic resonances at visible frequencies
Nano Letters 15 (2), 1368-1373 (2015) (get article)

Kocabey, S., Meinl, H., MacPherson, I. S., Cassinelli, V., Manetto, A., Rothenfusser, S., Liedl, T., Lichtenegger, F. S.
Cellular uptake of tile-assembled DNA nanotubes
Nanomaterials 5 (1), 47-60 (2015) (get article)


A. Kuzyk, R. Schreiber, H. Zhang, A. O. Govorov, T. Liedl, N. Liu
"Reconfigurable 3D Plasmonic Metamolecules"
Nature Materials 13, 862-866 (2014) (download pdf)

V. V. Thacker, L. O. Herrmann, D. O. Sigle, T. Zhang, T. Liedl, J. J. Baumberg, U. F. Keyser
"DNA Origami Based Assembly of Gold Nanoparticle Dimers for Surface-Enhanced Raman Scattering"
Nature Communications 5: 3448 (2014) (download pdf)

P. Kühler, E. Roller, R. Schreiber, T. Liedl, T. Lohmüller, J. Feldmann
"Plasmonic DNA-Origami Nanoantennas for Surface-Enhanced Raman Spectroscopy"
Nano Letters 14 (5), 2914-2919 (2014) (get article)

S. S. Simmel, P. C. Nickels, T. Liedl
"Wireframe and Tensegrity DNA Nanostructures"
Accounts of Chemical Research 47 (6), 1691-1699 (2014) (get article)

P. C. Nickels, Y. Ke, R. Jungmann, D. M. Smith, M. Leichsenring, W. M. Shih, T. Liedl, B. Högberg
"DNA Origami Structures Directly Assembled from Intact Bacteriophages"
Small 10 (9), 1765-1769 (2014) (get article)

R. Schreiber, J. Do, E. Roller, T. Zhang, V. J. Schüller, P. C. Nickels, J. Feldmann, T. Liedl
"Hierarchical Assembly of Metal Nanoparticles, Quantum Dots and Organic Dyes Using DNA Origami Scaffolds"
Nature Nanotechnology 9, 74-78 (2014) (download pdf)


R. Schreiber, N. Luong, Z. Fan, A. Kuzyk, P. C. Nickels, T. Zhang, D. M. Smith, B. Yurke, W. Kuang, A. O. Govorov, T. Liedl
"Chiral plasmonic DNA nanostructures with switchable circular dichroism"
Nature Communications 4: 2948 (2013) (download pdf)

D. Schiffels, T. Liedl, D. K. Fygenson
"Nanoscale Structure and Microscale Stiffness of DNA Nanotubes"
ACS Nano 7 (8), 6700-6710 (2013) (get article)

J. J. Schmied, C. Forthmann, E. Pibiri, B. Lalkens, P. Nickels, T. Liedl P. Tinnefeld
"DNA Origami Nanopillars as Standards for Three-dimensional Superresolution Microscopy"
Nano Letters 13, 781-785 (2013) (get article)

D. M. Smith , V. J. Schüller , C. Engst , J. O. Rädler , T. Liedl
"Nucleic acid nanostructures for biomedical applications"
Nanomedicine 8, 105-121 (2013) (get article)

N. A. W. Bell, V. V. Thacker, S. Hernandez-Ainsa, M. E. Fuentes-Perez, F. Moreno-Herrero, T. Liedl, U. F. Keyser
"Multiplexed ionic current sensing with glass nanopores"
Lab on a Chip 13, 1859-1862 (2013) (get article)

Z. Fan, H. Zhang, R. Schreiber, T. Liedl, G. Markovich, V. A. Gérard, Y. K. Gun’ko, A. O. Govorov
"Chiral Nanostructures with Plasmon and Exciton Resonances" In Book: “Singular and Chiral Nanoplasmonics”,
Edited by S. V. Boriskina and N. Zheludev, Pan Stanford Publishing.


H. Said , V. J. Schüller , F. J. Eber , C. Wege , T. Liedl and C. Richert
M1.3 – a small scaffold for DNA origami
Nanoscale 5, 284-290 (2012) (get pdf)

J. Do, R. Schreiber, A.A. Lutich, T. Liedl, J. Rodríguez-Fernández, J. Feldmann
Design and Optical Trapping of a Biocompatible Propeller-like Nanoscale Hybrid
Nano Letters 12, 5008-5013 (2012) (get article)

G. P. Acuna, M. Bucher, I. H. Stein,C. Steinhauer, A. Kuzyk, P. Holzmeister, R. Schreiber, A. Moroz, F. D. Stefani, T. Liedl, F. C. Simmel, P. Tinnefeld
Distance Dependence of Single-Fluorophore Quenching by Gold Nanoparticles Studied on DNA Origami
ACS Nano 6, 3189-3195 (2012) (get article)

A. Kuzyk, R. Schreiber, Z. Fan, G. Pardatscher, E. Roller, A. Högele, F. C. Simmel, A. O. Govorov, T. Liedl
DNA-based self-assembly of chiral plasmonic nanostructures with tailored optical response
Nature 483, 311-314 (2012) (download pdf)

N. A. W. Bell, C. R. Engst, M. Ablay, G. Divitini, C. Ducati, T. Liedl, and U. F. Keyser
DNA Origami Nanopores
Nano Letters 12, 512-517 (2012) (get article)
Research highlights in: Nature Nanotechnology (get article) and Nature Materials (get article)


V. J. Schüller, S. Heidegger, N. Sandholzer, P. C. Nickels, N. A. Suhartha, S. Endres, C. Bourquin, and T. Liedl
Cellular Immunostimulation by CpG-Sequence-Coated DNA Origami Structures
ACS Nano 5, 9696-9702 (2011) (get article)

D. J. Kauert, T. Kurth, T. Liedl and R. Seidel
Direct Mechanical Measurements Reveal the Material Properties of Three-Dimensional DNA Origami
Nano Letters 11, 5558-5563 (2011) (get article)

D. M. Smith, V. Schüller, C. Forthmann, R. Schreiber, P. Tinnefeld, and T. Liedl,
A Structurally Variable Hinged Tetrahedron Framework from DNA Origami
Journal of Nucleic Acids 2011: 360954, 9 pages (2011) (get article)

R. Schreiber, S. Kempter, S. Holler, V. Schüller, D. Schiffels, S. S. Simmel, P. C. Nickels and T. Liedl
DNA Origami-Templated Growth of Arbitrarily Shaped Metal Nanoparticles
Small 7, 1795-1799 (2011) (get article)

I. Stein, V. Schüller, P. Böhm, P. Tinnefeld and T. Liedl
Single-Molecule FRET Ruler Based on Rigid DNA Origami Blocks
ChemPhysChem, 12, 689-695 (2011) (get article)


T. Liedl, B. Högberg, J. Tytell, D. E. Ingber, and W. M. Shih
Self-assembly of 3D prestressed tensegrity structures from DNA
Nature Nanotechnology 5, 520–524 (2010) (download pdf)


B. Högberg, T. Liedl, and W. M. Shih
Folding DNA origami from a double-stranded source of scaffold
J. Am. Chem. Soc. 131, 9154–9155 (2009) (get article)

S. M. Douglas, H. Dietz, T. Liedl, B. Högberg, F. Graf, and W. M. Shih
Self-assembly of DNA into nanoscale three-dimensional shapes
Nature 459, 414–418 (2009) (download pdf)


R. Jungmann, T. Liedl, T. L. Sobey, W. M. Shih, and F. C. Simmel
Isothermal assembly of DNA origami structures using denaturing agents
J. Am. Chem. Soc. 130, 10062-10063 (2008) (get article)

S.K. Kufer, E. Puchner, H. Gumpp, T. Liedl, and H.E. Gaub
Single-Molecule Cut-and-Paste Surface Assembly
Science 319, 594-596 (2008) (download pdf)


T. Liedl, H. Dietz, B. Yurke, and F. C. Simmel
Controlled trapping and release of quantum dots in a DNA-linked hydrogel
Small 3, 1688-1690 (2007) (get article)

T. Liedl and F. C. Simmel
Determination of DNA melting temperatures in diffusion-generated chemical gradients
Analytical Chemistry 79, 5212-5216 (2007) (get article)

R. Sperling, T. Liedl, S. Duhr, S. Kudera, M. Zanella, D. Braun, and W. J. Parak
Size determination of (bio-) conjugated water-soluble colloidal nanoparticles - a comparison of different techniques
J. Phys. Chem. C 111, 11552 -11559 (2007) (get article)

C. A. J. Lin, T. Liedl, R. Sperling, M. T. Fernandez-Arguelles, J. M. Costa-Fernandez, R. Pereiro, A. Sanz-Medel, W. H. Chang, and W. J. Parak
Bioanalytics and biolabeling with semiconductor nanoparticles (quantum dots)
J. Mater. Chem 17, 1343-1346 (2007) (get pdf)


T. Liedl, M. Olapinski, and F. C. Simmel
A surface-bound DNA switch driven by a chemical oscillator
Angewandte Chemie - International Edition 45, 5007-5010 (2006) (get article)

A. Genovesio, T. Liedl, V. Emiliani, W. J. Parak, M. Coppey-Moisan, and J. C. Olivo-Marin
Multiple particle tracking in 3-D+t microscopy: Method and application to the tracking of endocytosed quantum dots
IEEE Transactions On Image Processing 15, 1062-1070 (2006) (download abstract) (get article)


T. Liedl and F. C. Simmel
Switching the conformation of a DNA molecule with a chemical oscillator
Nano Letters 5, 1894-1898 (2005) (get article)

T. Liedl, S. Keller, F. C. Simmel, J. O. Radler, and W. J. Parak
Fluorescent nanocrystals as colloidal probes in complex fluids measured by fluorescence correlation spectroscopy
Small 1, 997-1003 (2005) (get article)

G. B. Sukhorukov, A. L. Rogach, B. Zebli, T. Liedl, A. G. Skirtach, K. Kohler, A. A. Antipov, N. Gaponik, A. S. Susha, M. Winterhalter, and W. J. Parak
Nanoengineered polymer capsules: Tools for detection, controlled delivery, and site-specific manipulation
Small 1, 194-200 (2005) (get article)

C. Kirchner, T. Liedl, S. Kudera, T. Pellegrino, A. M. Javier, H. E. Gaub, S. Stolzle, N. Fertig and W. J. Parak
Cytotoxicity of colloidal CdSe and CdSe/ZnS nanoparticles
Nano Letters 5, 331-338 (2005) (get article)


T. Pellegrino, L. Manna, S. Kudera, T. Liedl, D. Koktysh, A. L. Rogach, S. Keller, J. Radler, G. Natile, and W. J. Parak
Hydrophobic nanocrystals coated with an amphiphilic polymer shell: A general route to water soluble nanocrystals
Nano Letters 4, 703-707 (2004) (get article)


T. Liedl, T. Sobey, and F. C. Simmel
DNA-based nanodevices
Nano Today 2, 36-41 (2007) (get article)

T. Pellegrino, S. Kudera, T. Liedl, A. M. Javier, L. Manna, and W. J. Parak
On the development of colloidal nanoparticles towards multifunctional structures and their possible use for biological applications
Small 1, 48-63 (2005) (get article)

T. Liedl, T. Pellegrino, and W. J. Parak
Biological Applications of colloidal Nanocrystals
New Drugs 2, 14-16 (2005)