Soft Condensed Matter Group
print


Breadcrumb Navigation


Content

Welcome to the Rädler Group

If you are interested in doing your bachelor thesis directly in the group of Joachim Rädler please contact Alexandra Murschhauser. For a master thesis in the Rädler group, please contact Janina Lange.

  • Supported Membranes and Artificial Micro-Niches

    supported

    Supported membranes are versatile biomimetic interfaces. We study the structure and dynamics of supported membranes on various solid supports in collaboration with the group of Bert Nickel. The control of fluidity, spacing and lateral organisation is a current research challenge. more

  • Biopolymers and Blood Proteins

    fokus-dna

    Biopolymers have unique properties with respect to their self-assembly, conformational dynamics, transport and interactions with interfaces. Fluorescently labeled biopolymers and proteins can be studied by Quantitative Fluorescence Microscopy (QFM) and Fluorescence Correlations Spectroscopy (FCS). more

  • Gene Delivery and Programmed Manipulation of Cells

    lipiddna

    In gene and siRNA based therapy, therapeutic benefits rely on the efficient transfer of foreign nucleic acids into cells. We investigate synthetic complexes capable of readily carrying nucleic acid across the cell membrane. The self-assembly, size and structure of lipid- and polycation-DNA complexes, known respectively as lipoplexes and polyplexes, are studied. We also endeavor to quantify and model transfection at the single cell level using GFP reporter and single cell time-lapse microscopy. more

  • Single Cell Response and Decision Making

    Heterogenität25min

    One of the most prominent phenomena in biological systems is their capability to adopt to environmental changes. The underlying signaling networks are highly optimized since cellular decision making is ultimately linked to survival. A common observation is the fact that cell decisions are to some degree heterogeneous among a isogenic population. This fact can be traced back to natural number fluctuations in signalling elements. more

  • Collective Cell Migration in Microstructured Environments

    cellmigration

    Collective cell migration is a key element in morphogenesis, cancer formation and wound healing. The multicellular dynamics of epithelial cell layers were studied in experiment and theory over the last years. Yet little is known about cell patches of finite size that should lead over from single cell behavior to collective motion. Here we study the migration and proliferation of small assemblies of epithelial cells more

  • Nanoparticle-Cell Interactions

    probes00

    The interaction of nanoparticles with living cells is important with respect to both nanomedicine as well as nanotoxicity. We study various aspects of nanoparticles (NPs). The transport of NPs in biopolymer solutions, the adsorption of proteins to NPs, the uptake of NPs by cells and the interference of NPs with cellular signalling and cell death. more

  • Members